{"created":"2023-05-15T14:33:03.635648+00:00","id":544,"links":{},"metadata":{"_buckets":{"deposit":"35f71419-f458-4f2c-a7eb-ad84c30b16a6"},"_deposit":{"created_by":8,"id":"544","owners":[8],"pid":{"revision_id":0,"type":"depid","value":"544"},"status":"published"},"_oai":{"id":"oai:uekusa.repo.nii.ac.jp:00000544","sets":["1","1:91"]},"author_link":["999"],"control_number":"544","item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-03-31","bibliographicIssueDateType":"Issued"},"bibliographicNumberOfPages":"81","bibliographicPageEnd":"65","bibliographicPageStart":"59","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"植草学園大学研究紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Bulletin of Education and Health Science, Uekusa-Gakuen University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"片頭痛の実態は重い神経障害であり，人口の約 10％が日常的に悩んでいる。国際頭痛学会では，4 〜 72時間続く再発性の原発性頭痛障害を片頭痛と定義している。頭痛は片側性かつ脈動性が多く，中等度から重度の強さが日常的な身体活動によって悪化し，めまいや悪心あるいは羞明および音過敏を伴うことが多い。片頭痛には周期的な病態の変化があり，「予兆期」，「前兆期」，「頭痛発作期」，「postdrome（後発症状）」と移行する。発作の約 3 日前から体調の変化を感じる予兆期には視床下部，脳幹，大脳辺縁系，および特定の皮質領域が活性化し，約 3 分の 1 の患者は視覚，感覚，言語または脳幹の障害からなる前兆を伴う時期があるが，その際大脳皮質に特有の“spreading depression (CSD）”が生じる。Postdrome ではめまい，倦怠感，身体の痛み，集中力の欠如，抑うつ症状などが残存し，これが仕事などに対する意欲の低下にもつながる問題となっている。\n片頭痛の発症メカニズムは 1938 年から研究され始め，現在も治療薬開発のために世界各国で研究が続いているが，近年になって分子生物学や画像解析技術の進歩により，ようやくその病態解明に光明が現れている","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Migraine is a serious neurological disorder, from which approximately 10 percent of the population suffers on a daily basis. The International Headache Society defines recurrent primary headache disorder, which lasts 4 to 72 hours, as migraine. Headaches are often unilateral and pulsating, while moderate to severe strength is exacerbated by routine physical activity, and often accompanied by dizziness or nausea, or photophobia and phonophobia. Migraine has periodic pathophysiology changes and migrates through premonitory phase, “aura”, headache attack period, and postdrome. The premonitory phase includes a complex interplay between the hypothalamus, the brain stem, and certain cortical regions. In about one-third of the patients this is accompanied by aura consisting of visual, sensory, language or brainstem disorders, at which “spreading depression (CSD)” specific to the cerebral cortex occurs. In postdrome dizziness, malaise, physical pain, lack of concentration, and depressive symptoms remain, which can lead to a decline in motivation for work and so on.\n　The mechanism of migraine onset began to be studied in 1938 and the development of treatment is still being studied globally, while in recent years advances in molecular biology and imaging analytic technology have cast light on its pathophysiology.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"植草学園大学"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12412714","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"18835988","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAlternatives":[{"creatorAlternative":"MAEDA, Hitoshi","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"前田, 仁士","creatorNameLang":"ja"},{"creatorName":"MAEDA, Hitoshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"マエダ","familyNameLang":"ja"}],"givenNames":[{"givenName":"ヒトシ","givenNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"999","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-03-23"}],"displaytype":"detail","filename":"06 前田（59-65白）.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"label":"uedai13_06_h_maeda","url":"https://uekusa.repo.nii.ac.jp/record/544/files/06 前田（59-65白）.pdf"},"version_id":"601c90f9-4a8c-4fe7-b126-52228d9932c6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"予兆期","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"前兆","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"閃輝暗点","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"premonitory phase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"aura","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"scintillating scotoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"CSD","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"postdrome","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"片頭痛とはどういう病気なのか : 一般に誤解されていることを最新の知見を交えて説く","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"片頭痛とはどういう病気なのか : 一般に誤解されていることを最新の知見を交えて説く","subitem_title_language":"ja"},{"subitem_title":"What is migraine? “resolving general misunderstandings with the latest knowledge”","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"8","path":["1","91"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-03-24"},"publish_date":"2021-03-24","publish_status":"0","recid":"544","relation_version_is_last":true,"title":["片頭痛とはどういう病気なのか : 一般に誤解されていることを最新の知見を交えて説く"],"weko_creator_id":"8","weko_shared_id":-1},"updated":"2023-11-14T07:05:51.651835+00:00"}